This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Glycogen Phosphorylase
From Proteopedia
| Line 5: | Line 5: | ||
{{STRUCTURE_1z6q| PDB=1z6q | SCENE= }} | {{STRUCTURE_1z6q| PDB=1z6q | SCENE= }} | ||
| - | = | + | =Introduction<ref name="gp">PMID: 15214781 </ref>= |
Glycogen phosphorylase catalyzes the hydrolysis of glycogen to generate glucose-1-phosphate and is considered the rate limiting step in the degradation of glycogen. The glucose-1-phophate is then further degraded via the pathway of glycolysis. There is both muscle and liver glycogen phosphorylase; muscle glycogen phosphorylase is present to degrade glycogen to forms of energy by means of glycolysis during muscle contractions. | Glycogen phosphorylase catalyzes the hydrolysis of glycogen to generate glucose-1-phosphate and is considered the rate limiting step in the degradation of glycogen. The glucose-1-phophate is then further degraded via the pathway of glycolysis. There is both muscle and liver glycogen phosphorylase; muscle glycogen phosphorylase is present to degrade glycogen to forms of energy by means of glycolysis during muscle contractions. | ||
=Function= | =Function= | ||
Revision as of 03:32, 26 March 2010
| Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. Andrea Gorrell. |
Contents |
Introduction[1]
Glycogen phosphorylase catalyzes the hydrolysis of glycogen to generate glucose-1-phosphate and is considered the rate limiting step in the degradation of glycogen. The glucose-1-phophate is then further degraded via the pathway of glycolysis. There is both muscle and liver glycogen phosphorylase; muscle glycogen phosphorylase is present to degrade glycogen to forms of energy by means of glycolysis during muscle contractions.
Function
type stuff here
Structure and Mechanism
References
- ↑ Kristiansen M, Andersen B, Iversen LF, Westergaard N. Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site. J Med Chem. 2004 Jul 1;47(14):3537-45. PMID:15214781 doi:10.1021/jm031121n
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Amy Chahal, Ann Taylor, Alexander Berchansky, Joel L. Sussman, Riley Hicks, Andrea Gorrell, David Canner
