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3lfn

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Revision as of 07:09, 7 April 2010

Image:3lfn.png

Template:STRUCTURE 3lfn

Crystal structure of CDK2 with SAR57, an aminoindazole type inhibitor

Template:ABSTRACT PUBMED 20167481

About this Structure

3LFN is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lesuisse D, Dutruc-Rosset G, Tiraboschi G, Dreyer MK, Maignan S, Chevalier A, Halley F, Bertrand P, Burgevin MC, Quarteronet D, Rooney T. Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1985-9. Epub 2010 Jan 25. PMID:20167481 doi:10.1016/j.bmcl.2010.01.114

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