3is9

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3is9.jpg|left|200px]]
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The entry 3is9 is ON HOLD until Paper Publication
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{{STRUCTURE_3is9| PDB=3is9 | SCENE= }}
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Authors: Ho, W.C., Bauman, J.D., Das, K., Arnold, E.
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===Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate).===
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Description: Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate).
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 24 08:34:50 2010''
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{{ABSTRACT_PUBMED_19775161}}
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==About this Structure==
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3IS9 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_bh10 Human immunodeficiency virus type 1 bh10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IS9 OCA].
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==Reference==
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<ref group="xtra">PMID:19775161</ref><references group="xtra"/>
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[[Category: Human immunodeficiency virus type 1 bh10]]
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[[Category: Arnold, E.]]
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[[Category: Bauman, J D.]]
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[[Category: Das, K.]]
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[[Category: Ho, W C.]]
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[[Category: Adam]]
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[[Category: Aid]]
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[[Category: Aspartyl protease]]
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[[Category: Cell membrane]]
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[[Category: Cytoplasm]]
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[[Category: Dna integration]]
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[[Category: Dna recombination]]
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[[Category: Dna-directed dna polymerase]]
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[[Category: Endonuclease]]
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[[Category: Hiv]]
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[[Category: Hydrolase]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Multifunctional enzyme]]
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[[Category: Myristate]]
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[[Category: Nnrti]]
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[[Category: Nonnucleoside inhibitor]]
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[[Category: Nuclease]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Nucleus]]
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[[Category: P51/p66]]
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[[Category: Phosphoprotein]]
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[[Category: Protease]]
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[[Category: Rna-binding]]
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[[Category: Rna-directed dna polymerase]]
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[[Category: Transferase]]
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[[Category: Transferase-hydrolase complex]]
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[[Category: Viral nucleoprotein]]
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[[Category: Virion]]
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[[Category: Zinc]]
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[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 7 10:40:22 2010''

Revision as of 07:40, 7 April 2010

Image:3is9.jpg

Template:STRUCTURE 3is9

Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate).

Template:ABSTRACT PUBMED 19775161

About this Structure

3IS9 is a 2 chains structure with sequences from Human immunodeficiency virus type 1 bh10. Full crystallographic information is available from OCA.

Reference

  • Cullen MD, Ho WC, Bauman JD, Das K, Arnold E, Hartman TL, Watson KM, Buckheit RW, Pannecouque C, De Clercq E, Cushman M. Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase. J Med Chem. 2009 Oct 22;52(20):6467-73. PMID:19775161 doi:10.1021/jm901167t

Page seeded by OCA on Wed Apr 7 10:40:22 2010

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