3exo

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===Crystal structure of BACE1 bound to inhibitor===
===Crystal structure of BACE1 bound to inhibitor===
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The line below this paragraph, {{ABSTRACT_PUBMED_19036583}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 19036583 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19036583}}
==About this Structure==
==About this Structure==
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3EXO is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXO OCA].
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3EXO is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXO OCA].
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==Reference==
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<ref group="xtra">PMID:19036583</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 11:36:09 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 08:58:07 2010''

Revision as of 05:58, 14 April 2010

Template:STRUCTURE 3exo

Crystal structure of BACE1 bound to inhibitor

Template:ABSTRACT PUBMED 19036583

About this Structure

3EXO is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Steele TG, Hills ID, Nomland AA, de Leon P, Allison T, McGaughey G, Colussi D, Tugusheva K, Haugabook SJ, Espeseth AS, Zuck P, Graham SL, Stachel SJ. Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement. Bioorg Med Chem Lett. 2009 Jan 1;19(1):17-20. Epub 2008 Nov 13. PMID:19036583 doi:10.1016/j.bmcl.2008.11.027

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