3lj3

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(New page: '''Unreleased structure''' The entry 3lj3 is ON HOLD Authors: Bard, J., Svenson, K. Description: PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor ''Page seeded by [http://...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3lj3.jpg|left|200px]]
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The entry 3lj3 is ON HOLD
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The line below this paragraph, containing "STRUCTURE_3lj3", creates the "Structure Box" on the page.
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{{STRUCTURE_3lj3| PDB=3lj3 | SCENE= }}
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Authors: Bard, J., Svenson, K.
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===PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor===
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Description: PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 3 09:20:13 2010''
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{{ABSTRACT_PUBMED_20188552}}
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==About this Structure==
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3LJ3 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJ3 OCA].
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==Reference==
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<ref group="xtra">PMID:20188552</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
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[[Category: Bard, J.]]
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[[Category: Svenson, K.]]
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[[Category: Atp-binding]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 09:37:24 2010''

Revision as of 06:37, 14 April 2010

Image:3lj3.jpg

Template:STRUCTURE 3lj3

PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor

Template:ABSTRACT PUBMED 20188552

About this Structure

3LJ3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tsou HR, MacEwan G, Birnberg G, Grosu G, Bursavich MG, Bard J, Brooijmans N, Toral-Barza L, Hollander I, Mansour TS, Ayral-Kaloustian S, Yu K. Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran- 3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR). Bioorg Med Chem Lett. 2010 Apr 1;20(7):2321-5. Epub 2010 Feb 2. PMID:20188552 doi:10.1016/j.bmcl.2010.01.135

Page seeded by OCA on Wed Apr 14 09:37:24 2010

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