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3le8

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3le8.jpg|left|200px]]
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The entry 3le8 is ON HOLD until Paper Publication
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{{STRUCTURE_3le8| PDB=3le8 | SCENE= }}
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Authors: Silvestre, H.L., Hung, A.W., Sledz, P., Ciulli, A., Blundell, T.L., Abell, C.
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===Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.70 Angstrom resolution in complex with 2-(2-((benzofuran-2-carboxamido)methyl)-5-methoxy-1H-indol-1-yl)acetic acid===
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Description: Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.70 Angstrom resolution in complex with 2-(2-((benzofuran-2-carboxamido)methyl)-5-methoxy-1H-indol-1-yl)acetic acid
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 15:25:55 2010''
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(as it appears on PubMed at http://www.pubmed.gov), where 20232910 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20232910}}
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==About this Structure==
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3LE8 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LE8 OCA].
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==Reference==
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<ref group="xtra">PMID:20232910</ref><references group="xtra"/>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Abell, C.]]
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[[Category: Blundell, T L.]]
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[[Category: Ciulli, A.]]
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[[Category: Hung, A W.]]
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[[Category: Silvestre, H L.]]
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[[Category: Sledz, P.]]
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[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
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[[Category: Fragment linking]]
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[[Category: Fragment-based drug discovery]]
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[[Category: Iloe]]
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[[Category: Ligase]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Pantothenate biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 09:37:48 2010''

Revision as of 06:37, 14 April 2010

Image:3le8.jpg

Template:STRUCTURE 3le8

Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.70 Angstrom resolution in complex with 2-(2-((benzofuran-2-carboxamido)methyl)-5-methoxy-1H-indol-1-yl)acetic acid

Template:ABSTRACT PUBMED 20232910

About this Structure

3LE8 is a 2 chains structure with sequences from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Sledz P, Silvestre HL, Hung AW, Ciulli A, Blundell TL, Abell C. Optimization of the interligand overhauser effect for fragment linking: application to inhibitor discovery against Mycobacterium tuberculosis pantothenate synthetase. J Am Chem Soc. 2010 Apr 7;132(13):4544-5. PMID:20232910 doi:10.1021/ja100595u

Page seeded by OCA on Wed Apr 14 09:37:48 2010

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