3lhj

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3lhj.jpg|left|200px]]
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The entry 3lhj is ON HOLD until Paper Publication
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{{STRUCTURE_3lhj| PDB=3lhj | SCENE= }}
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Authors: Mohr, C., Jordan, S.
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===Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor.===
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Description: Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor.
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 16:58:35 2010''
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(as it appears on PubMed at http://www.pubmed.gov), where 20218619 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20218619}}
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==About this Structure==
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3LHJ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LHJ OCA].
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==Reference==
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<ref group="xtra">PMID:20218619</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Mitogen-activated protein kinase]]
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[[Category: Jordan, S.]]
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[[Category: Mohr, C.]]
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[[Category: Alternative splicing]]
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[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 09:42:51 2010''

Revision as of 06:42, 14 April 2010

Image:3lhj.jpg

Template:STRUCTURE 3lhj

Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor.

Template:ABSTRACT PUBMED 20218619

About this Structure

3LHJ is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Pettus LH, Wurz RP, Xu S, Herberich B, Henkle B, Liu Q, McBride HJ, Mu S, Plant MH, Saris CJ, Sherman L, Wong LM, Chmait S, Lee MR, Mohr C, Hsieh F, Tasker AS. Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase. J Med Chem. 2010 Apr 8;53(7):2973-85. PMID:20218619 doi:10.1021/jm100095x

Page seeded by OCA on Wed Apr 14 09:42:51 2010

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