User talk:Johan sunryd/sandbox 1
From Proteopedia
(Difference between revisions)
(New page: ER Man 1 ER Mannosidase 1 is a type II ER membrane protein that. EMechanism of class 1 (glycosylhydrolase family 47) Alpha-mannosidases involved ...) |
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[[Image:intactModelLargeText.jpg|frame|ER Man 1]] | [[Image:intactModelLargeText.jpg|frame|ER Man 1]] | ||
| - | + | Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins. | |
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| - | Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 | + | |
Revision as of 01:39, 26 April 2010
ER Man 1
Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.
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Catalytic Site
The spinning protein () ) is a highlight of the catalytic residues of ERMan1.
Molecular Playground banner: A catalytic timer for protein degradation.
