1qn2
From Proteopedia
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| - | [[Image:1qn2. | + | [[Image:1qn2.jpg|left|200px]]<br /><applet load="1qn2" size="450" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1qn2" size="450" color="white" frame="true" align="right" spinBox="true" | + | |
caption="1qn2, resolution 2.01Å" /> | caption="1qn2, resolution 2.01Å" /> | ||
'''CYTOCHROME CH FROM METHYLOBACTERIUM EXTORQUENS'''<br /> | '''CYTOCHROME CH FROM METHYLOBACTERIUM EXTORQUENS'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1QN2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methylobacterium_extorquens Methylobacterium extorquens] with HEC as [http://en.wikipedia.org/wiki/ligand ligand]. | + | 1QN2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methylobacterium_extorquens Methylobacterium extorquens] with HEC as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=AC1:Hec Binding Site For Chain A'>AC1</scene>, <scene name='pdbsite=AC2:Hec Binding Site For Chain B'>AC2</scene> and <scene name='pdbsite=AC3:Hec Binding Site For Chain C'>AC3</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QN2 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: electron transport]] | [[Category: electron transport]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 17:57:34 2007'' |
Revision as of 15:47, 18 December 2007
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CYTOCHROME CH FROM METHYLOBACTERIUM EXTORQUENS
Overview
Cytochrome cH is the electron donor to the oxidase in methylotrophic, bacteria. Its amino acid sequence suggests that it is a typical Class 1, cytochrome c, but some features of the sequence indicated that its, structure might be of special interest. The structure of oxidized, cytochrome cH has been solved to 2.0 A resolution by X-ray diffraction. It, has the classical tertiary structure of the Class 1 cytochromes c but, bears a closer gross resemblance to mitochondrial cytochrome c than to the, bacterial cytochrome c2. The left-hand side of the haem cleft is unique;, in particular, it is highly hydrophobic, the usual water is absent, and, the "conserved" Tyr67 is replaced by tryptophan. A number of features of, the structure demonstrate that the usual hydrogen bonding network, involving water in the haem channel is not essential and that other, mechanisms may exist for modulation of redox potentials in this, cytochrome.
About this Structure
1QN2 is a Single protein structure of sequence from Methylobacterium extorquens with HEC as ligand. Known structural/functional Sites: , and . Full crystallographic information is available from OCA.
Reference
The molecular structure of an unusual cytochrome c2 determined at 2.0 A; the cytochrome cH from Methylobacterium extorquens., Read J, Gill R, Dales SL, Cooper JB, Wood SP, Anthony C, Protein Sci. 1999 Jun;8(6):1232-40. PMID:10386873
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