3bjm

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==About this Structure==
==About this Structure==
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3BJM is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BJM OCA].
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3BJM is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BJM OCA].
==Reference==
==Reference==
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[[Category: Exopeptidase]]
[[Category: Exopeptidase]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Protease]]
[[Category: Protease]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:48:17 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 11:16:11 2010''

Revision as of 08:16, 28 April 2010

Image:3bjm.png

Template:STRUCTURE 3bjm

Crystal structure of human DPP-IV in complex with (1S,3S, 5S)-2-[(2S)-2-AMINO-2-(3-HYDROXYTRICYCLO[3.3.1.13,7]DEC-1- YL)ACETYL]-2-AZABICYCLO[3.1.0]HEXANE-3-CARBONITRILE (CAS), (1S,3S,5S)-2-((2S)-2-AMINO-2-(3-HYDROXYADAMANTAN-1- YL)ACETYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBONITRILE (IUPAC), OR BMS-477118

Template:ABSTRACT PUBMED 18227430

About this Structure

3BJM is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Metzler WJ, Yanchunas J, Weigelt C, Kish K, Klei HE, Xie D, Zhang Y, Corbett M, Tamura JK, He B, Hamann LG, Kirby MS, Marcinkeviciene J. Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation. Protein Sci. 2008 Feb;17(2):240-50. PMID:18227430 doi:17/2/240

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