1qox
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 1QOX is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_circulans Bacillus circulans]]. Active as [[http://en.wikipedia.org/wiki/ | + | 1QOX is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_circulans Bacillus circulans]]. Active as [[http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21]]. Structure known Active Sites: CAA, CAB, CAC, CAD, CAE, CAF, CAG, CAH, CAI, CAJ, CAK, CAL, CAM, CAN, CAO and CAP. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QOX OCA]]. |
==Reference== | ==Reference== | ||
The crystal structure of beta-glucosidase from Bacillus circulans sp. alkalophilus: ability to form long polymeric assemblies., Hakulinen N, Paavilainen S, Korpela T, Rouvinen J, J Struct Biol. 2000 Feb;129(1):69-79. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10675298 10675298] | The crystal structure of beta-glucosidase from Bacillus circulans sp. alkalophilus: ability to form long polymeric assemblies., Hakulinen N, Paavilainen S, Korpela T, Rouvinen J, J Struct Biol. 2000 Feb;129(1):69-79. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10675298 10675298] | ||
[[Category: Bacillus circulans]] | [[Category: Bacillus circulans]] | ||
| + | [[Category: Beta-glucosidase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Hakulinen, N.]] | [[Category: Hakulinen, N.]] | ||
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[[Category: hydrolase]] | [[Category: hydrolase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 10:37:00 2007'' |
Revision as of 08:32, 30 October 2007
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BETA-GLUCOSIDASE FROM BACILLUS CIRCULANS SP. ALKALOPHILUS
Overview
Family 1 of glycosyl hydrolases is a large and biologically important, group of enzymes. A new three-dimensional structure of this family, beta-glucosidase from Bacillus circulans sp. alkalophilus is reported, here. This is the first structure of beta-glucosidase from an alkaliphilic, organism. The model was determined by the molecular replacement method and, refined to a resolution of 2.7 A. The quaternary structure of B. circulans, sp. alkalophilus beta-glucosidase is an octamer and subunits of the, octamer show a similar (beta/alpha)(8) barrel fold to that previously, reported for other family 1 enzymes. The crystal structure suggested that, Cys169 in the active site is substituted. The Cys169 is located near the, putative acid/base catalyst Glu166 and it may contribute to the high pH, ... [(full description)]
About this Structure
1QOX is a [Single protein] structure of sequence from [Bacillus circulans]. Active as [Beta-glucosidase], with EC number [3.2.1.21]. Structure known Active Sites: CAA, CAB, CAC, CAD, CAE, CAF, CAG, CAH, CAI, CAJ, CAK, CAL, CAM, CAN, CAO and CAP. Full crystallographic information is available from [OCA].
Reference
The crystal structure of beta-glucosidase from Bacillus circulans sp. alkalophilus: ability to form long polymeric assemblies., Hakulinen N, Paavilainen S, Korpela T, Rouvinen J, J Struct Biol. 2000 Feb;129(1):69-79. PMID:10675298
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