User:Yadilette Rivera-Colon/Sandbox1
From Proteopedia
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[[Image:PPCA.jpg|frame|Human Lysosomal Protective Protein Cathepsin A]] | [[Image:PPCA.jpg|frame|Human Lysosomal Protective Protein Cathepsin A]] | ||
| - | The human protective protein cathepsin A forms a multi-enzyme complex with beta-galactosidase and neuraminidase in lysosomes. | + | The human protective protein cathepsin A forms a multi-enzyme complex with beta-galactosidase and neuraminidase in lysosomes. PPCA has so far two functions:a catalytic activity overlapping with that of Cathepsin A and a protective function towards lysosomal beta-galactosidase and neuraminidase. The stability and activity of the latter glycosidases depend on their interaction with PPCA> |
{{Clear}} | {{Clear}} | ||
Revision as of 23:05, 28 April 2010
Human Lysosomal Protective Protein Cathepsin A (PPCA)
The human protective protein cathepsin A forms a multi-enzyme complex with beta-galactosidase and neuraminidase in lysosomes. PPCA has so far two functions:a catalytic activity overlapping with that of Cathepsin A and a protective function towards lysosomal beta-galactosidase and neuraminidase. The stability and activity of the latter glycosidases depend on their interaction with PPCA>
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PPCA Glycosylation sites
PPCA, is synthesized as a 542 amino acid precursor with a molecular weight of 54kDa. and it dimerizes soon after synthesis. The sequence contains two glycosylation sites, Asn 117 and Asn 305. It also contains nine cysteines. The spinning protein ( ) is human protective protein with the glycosylation sites represented in stick model colored by atom.
