1szj
From Proteopedia
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| - | [[Image:1szj.gif|left|200px]]<br /> | + | [[Image:1szj.gif|left|200px]]<br /><applet load="1szj" size="450" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1szj" size="450" color="white" frame="true" align="right" spinBox="true" | + | |
caption="1szj, resolution 2.0Å" /> | caption="1szj, resolution 2.0Å" /> | ||
'''STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE FROM PALINURUS VERSICOLOR REFINED 2.0 ANGSTROM RESOLUTION'''<br /> | '''STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE FROM PALINURUS VERSICOLOR REFINED 2.0 ANGSTROM RESOLUTION'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1SZJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Palinurus_versicolor Palinurus versicolor] with SO4 and NAD as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] | + | 1SZJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Palinurus_versicolor Palinurus versicolor] with SO4 and NAD as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] Known structural/functional Site: <scene name='pdbsite=ACT:Active Site Residues CYS 149 And HIS 176'>ACT</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1SZJ OCA]. |
==Reference== | ==Reference== | ||
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[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 18:01:08 2007'' |
Revision as of 15:51, 18 December 2007
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STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE FROM PALINURUS VERSICOLOR REFINED 2.0 ANGSTROM RESOLUTION
Overview
When the active-site carboxymethylated D-glyceraldehyde-3-phosphate, dehydrogenase is irradiated with ultraviolet light in the presence of, NAD+, a fluorescent NAD derivative that is covalently linked to the enzyme, is obtained. A preliminary crystallographic study of this fluorescent, derivative, as well as of the native and the carboxymethylated enzymes, from Palinurus versicolor, showed that they are isomorphous and belong to, space group C2 as reported for the native enzyme from Palinurus vulgaris., The three forms of the enzyme, although they have identical unit cell, parameters, differ considerably in their diffraction patterns, indicating, marked differences in conformation in spite of the fact that they differ, chemically only in a restricted region around the active site.
About this Structure
1SZJ is a Single protein structure of sequence from Palinurus versicolor with SO4 and NAD as ligands. Active as Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating), with EC number 1.2.1.12 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Preliminary crystallographic studies of lobster D-glyceraldehyde-3-phosphate dehydrogenase and the modified enzyme carrying the fluorescent derivative., Song SY, Gao YG, Zhou JM, Tsou CL, J Mol Biol. 1983 Dec 5;171(2):225-8. PMID:6655693
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