User:Luis E Ramirez-Tapia/Sandbox 3
From Proteopedia
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| - | <applet load='1osl_19_1l1m_9_morph.pdb' size='350' frame='true' align='right' scene='Morphs/1osl_19_1l1m_9_morph/2' /></td></tr><tr><td bgcolor='#d0d0d0'>Morph: [[Lac repressor]] bending DNA as binding changes from non-specific to specific recognition of the operator sequence. [[Lac repressor#Morph_of_Conversion| Details]].</td></tr></table> | ||
<applet load='1osl_19_1l1m_9_morph.pdb' size='350' frame='true' align='right' scene='Morphs/1osl_19_1l1m_9_morph/2' /> | <applet load='1osl_19_1l1m_9_morph.pdb' size='350' frame='true' align='right' scene='Morphs/1osl_19_1l1m_9_morph/2' /> | ||
Revision as of 19:40, 30 April 2010
One of the CBI Molecules being studied in the University of Massachusetts Amherst Chemistry-Biology Interface Program at UMass Amherst and on display at the Molecular Playground. Template:STRUCTURE 3hvt Being the protein that gives their name to Retroviruses, Reverse Transcriptase is, in company of Protease and Integrase, the most important part of the protein system involved in the process of infection of viruses like HIV, MuLV and AMV, and has the unusual property of transcribing ssRNA into dsDNA going against the Central Dogma of Molecular Biology. Since its discovery in 1970, the study of its properties and mechanisms of action have been of high interest among the scientific community due to the unique properties that makes it an important medical target enzyme and important tool for genetic engineering applications like RT-PCR in the construction of cDNA libraries.
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