User:Adriana Kita/Sandbox 1
From Proteopedia
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Human beta-glucocerebrosidase (GCase) has seven Cys residues, four of which make two disulfide bonds. These two disufide bonds are both located in the N-terminal region of the protein and separated by only one amino acid. One of my current projects is using mass spectrometry to discern the disulfide connectivity in regions of a protein that are rich with Cys residues. | Human beta-glucocerebrosidase (GCase) has seven Cys residues, four of which make two disulfide bonds. These two disufide bonds are both located in the N-terminal region of the protein and separated by only one amino acid. One of my current projects is using mass spectrometry to discern the disulfide connectivity in regions of a protein that are rich with Cys residues. | ||
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'''GCase N-terminal residues 1-23:''' ''ARPCIPKSFGYSSVVCVCNATYCDS'' | '''GCase N-terminal residues 1-23:''' ''ARPCIPKSFGYSSVVCVCNATYCDS'' | ||
Disulfide Connectivity: ''C4-C16 & C18-C23'' | Disulfide Connectivity: ''C4-C16 & C18-C23'' | ||
Revision as of 00:05, 1 May 2010
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Description of GCB goes here.
I can describe more about GCB here.
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Disulfide Structure
Human beta-glucocerebrosidase (GCase) has seven Cys residues, four of which make two disulfide bonds. These two disufide bonds are both located in the N-terminal region of the protein and separated by only one amino acid. One of my current projects is using mass spectrometry to discern the disulfide connectivity in regions of a protein that are rich with Cys residues.
GCase N-terminal residues 1-23: ARPCIPKSFGYSSVVCVCNATYCDS
Disulfide Connectivity: C4-C16 & C18-C23
