3l0v
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
{{Seed}} | {{Seed}} | ||
| - | [[Image:3l0v. | + | [[Image:3l0v.png|left|200px]] |
<!-- | <!-- | ||
| Line 12: | Line 12: | ||
===Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket=== | ===Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket=== | ||
| + | |||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20172725}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20172725 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_20172725}} | ||
==About this Structure== | ==About this Structure== | ||
3L0V is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L0V OCA]. | 3L0V is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L0V OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20172725</ref><references group="xtra"/> | ||
[[Category: ADAM 17 endopeptidase]] | [[Category: ADAM 17 endopeptidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 24: | Line 33: | ||
[[Category: Protease]] | [[Category: Protease]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 11:11:44 2010'' |
Revision as of 08:11, 5 May 2010
Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket
Template:ABSTRACT PUBMED 20172725
About this Structure
3L0V is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Yu W, Guo Z, Orth P, Madison V, Chen L, Dai C, Feltz RJ, Girijavallabhan VM, Kim SH, Kozlowski JA, Lavey BJ, Li D, Lundell D, Niu X, Piwinski JJ, Popovici-Muller J, Rizvi R, Rosner KE, Shankar BB, Shih NY, Siddiqui MA, Sun J, Tong L, Umland S, Wong MK, Yang DY, Zhou G. Discovery and SAR of hydantoin TACE inhibitors. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1877-80. Epub 2010 Feb 4. PMID:20172725 doi:10.1016/j.bmcl.2010.01.148
Page seeded by OCA on Wed May 5 11:11:44 2010
