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User:Eran Hodis/Sandbox3
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| - | Two copies of each histone protein, | + | Two copies of each histone protein, <font color="gold">H2A</font>, <font color="red">H2B</font>, <font color="purple">H3</font>, and <font color="#00CC00">H4</font>, are assembled into an octameric disc. Although each monomer has an N-terminal tail that projects from the histone core, the structure at left shows only a single tail from one <span class="style9">H3</span> monomer. |
Revision as of 13:18, 12 May 2010
Nucleosome Structure
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Introduction
The nucleosome core particle contains two copies of each histone protein (H2A, H2B, H3 and H4) and 146 basepairs (bp) of superhelical DNA wrapped around this histone octamer. It represents the first order of DNA packaging in the nucleus and as such is the principal structure that determines DNA accessibility.
The Histone Octamer
Two copies of each histone protein, H2A, H2B, H3, and H4, are assembled into an octameric disc. Although each monomer has an N-terminal tail that projects from the histone core, the structure at left shows only a single tail from one H3 monomer.
