1v0k
From Proteopedia
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- | [[Image:1v0k. | + | [[Image:1v0k.jpg|left|200px]]<br /><applet load="1v0k" size="450" color="white" frame="true" align="right" spinBox="true" |
- | <applet load="1v0k" size="450" color="white" frame="true" align="right" spinBox="true" | + | |
caption="1v0k, resolution 1.03Å" /> | caption="1v0k, resolution 1.03Å" /> | ||
'''XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 5.8'''<br /> | '''XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 5.8'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
- | 1V0K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Active as [http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] | + | 1V0K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Active as [http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] Known structural/functional Site: <scene name='pdbsite=AC1:Xdn Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1V0K OCA]. |
==Reference== | ==Reference== | ||
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[[Category: xylanase]] | [[Category: xylanase]] | ||
- | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 18:20:37 2007'' |
Revision as of 16:10, 18 December 2007
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XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 5.8
Overview
The atomic resolution structures of xylobiose-derived isofagomine and, xylobiose-derived deoxynojirimycin in complex with the xylanase Xyn10A, from Streptomyces lividans reveal undistorted (4)C(1) chair conformed, sugars and, in the case of the deoxynojirimycin analogue, suggest unusual, pK(a) changes of the enzyme's catalytic machinery upon binding.
About this Structure
1V0K is a Single protein structure of sequence from Streptomyces lividans. Active as Endo-1,4-beta-xylanase, with EC number 3.2.1.8 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A., Gloster TM, Williams SJ, Roberts S, Tarling CA, Wicki J, Withers SG, Davies GJ, Chem Commun (Camb). 2004 Aug 21;(16):1794-5. Epub 2004 Jul 23. PMID:15306887
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