3kgt

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===V30M mutant human transthyretin (TTR) complexed with genistein (V30M:GEN) pH 7.5===
===V30M mutant human transthyretin (TTR) complexed with genistein (V30M:GEN) pH 7.5===
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{{ABSTRACT_PUBMED_20211733}}
==About this Structure==
==About this Structure==
3KGT is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KGT OCA].
3KGT is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KGT OCA].
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==Reference==
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<ref group="xtra">PMID:20211733</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Polikarpov, I.]]
[[Category: Polikarpov, I.]]
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[[Category: Trivella, D B.B.]]
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[[Category: Trivella, D B.]]
[[Category: Amyloid]]
[[Category: Amyloid]]
[[Category: Amyloidosis]]
[[Category: Amyloidosis]]
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[[Category: Ttr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 08:59:49 2010''

Revision as of 05:59, 20 May 2010

Image:3kgt.png

Template:STRUCTURE 3kgt

V30M mutant human transthyretin (TTR) complexed with genistein (V30M:GEN) pH 7.5

Template:ABSTRACT PUBMED 20211733

About this Structure

3KGT is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Trivella DB, Bleicher L, Palmieri Lde C, Wiggers HJ, Montanari CA, Kelly JW, Lima LM, Foguel D, Polikarpov I. Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding. J Struct Biol. 2010 Jun;170(3):522-31. Epub 2010 Mar 6. PMID:20211733 doi:10.1016/j.jsb.2010.03.002

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