3kfd

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===Ternary complex of TGF-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily===
===Ternary complex of TGF-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily===
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{{ABSTRACT_PUBMED_20207738}}
==Disease==
==Disease==
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==About this Structure==
==About this Structure==
3KFD is a 12 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFD OCA].
3KFD is a 12 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFD OCA].
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==Reference==
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<ref group="xtra">PMID:20207738</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Radaev, S.]]
[[Category: Radaev, S.]]
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[[Category: Tgf-beta receptor type-2]]
[[Category: Tgf-beta receptor type-2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 17:15:11 2010''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 09:05:07 2010''

Revision as of 06:05, 20 May 2010

Template:STRUCTURE 3kfd

Contents

Ternary complex of TGF-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily

Template:ABSTRACT PUBMED 20207738

Disease

Known disease associated with this structure: Colorectal cancer, hereditary nonpolyposis, type 6 OMIM:[190182], Esophageal cancer OMIM:[190182], Loeys-Dietz syndrome, type 1B OMIM:[190182], Loeys-Dietz syndrome, type 2B OMIM:[190182], Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]

About this Structure

3KFD is a 12 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Radaev S, Zou Z, Huang T, Lafer EM, Hinck AP, Sun PD. Ternary complex of transforming growth factor-beta1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily. J Biol Chem. 2010 May 7;285(19):14806-14. Epub 2010 Mar 5. PMID:20207738 doi:10.1074/jbc.M109.079921

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