3kb7

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3kb7.jpg|left|200px]]
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The entry 3kb7 is ON HOLD until Paper Publication
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{{STRUCTURE_3kb7| PDB=3kb7 | SCENE= }}
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Authors: Bossi, R.T.
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===Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor===
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Description: Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:52:36 2009''
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{{ABSTRACT_PUBMED_20397705}}
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==About this Structure==
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3KB7 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KB7 OCA].
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==Reference==
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<ref group="xtra">PMID:20397705</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Polo kinase]]
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[[Category: Bertrand, J A.]]
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[[Category: Bossi, R T.]]
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[[Category: Atp-binding]]
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[[Category: Cell cycle]]
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[[Category: Cell division]]
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[[Category: Kinase]]
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[[Category: Mitosis]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Protein kinase]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 09:40:29 2010''

Revision as of 06:40, 20 May 2010

Image:3kb7.jpg

Template:STRUCTURE 3kb7

Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor

Template:ABSTRACT PUBMED 20397705

About this Structure

3KB7 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Beria I, Ballinari D, Bertrand JA, Borghi D, Bossi RT, Brasca MG, Cappella P, Caruso M, Ceccarelli W, Ciavolella A, Cristiani C, Croci V, De Ponti A, Fachin G, Ferguson RD, Lansen J, Moll JK, Pesenti E, Posteri H, Perego R, Rocchetti M, Storici P, Volpi D, Valsasina B. Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors. J Med Chem. 2010 May 13;53(9):3532-51. PMID:20397705 doi:10.1021/jm901713n

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