2zir

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{{STRUCTURE_2zir| PDB=2zir | SCENE= }}
{{STRUCTURE_2zir| PDB=2zir | SCENE= }}
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===Crystal Structure of rat protein farnesyltransferase complexed with a bezoruran inhibitor and FPP===
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===Crystal Structure of rat protein farnesyltransferase complexed with a benzofuran inhibitor and FPP===
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==About this Structure==
==About this Structure==
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2ZIR is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIR OCA].
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2ZIR is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIR OCA].
==Reference==
==Reference==
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[[Category: Zinc]]
[[Category: Zinc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jan 18 09:12:08 2010''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:38:11 2010''

Revision as of 04:34, 26 May 2010

Template:STRUCTURE 2zir

Crystal Structure of rat protein farnesyltransferase complexed with a benzofuran inhibitor and FPP

Template:ABSTRACT PUBMED 19217288

About this Structure

2ZIR is a 2 chains structure with sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Asoh K, Kohchi M, Hyoudoh I, Ohtsuka T, Masubuchi M, Kawasaki K, Ebiike H, Shiratori Y, Fukami TA, Kondoh O, Tsukaguchi T, Ishii N, Aoki Y, Shimma N, Sakaitani M. Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1753-7. Epub 2009 Feb 11. PMID:19217288 doi:10.1016/j.bmcl.2009.01.074

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