This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3lu9
From Proteopedia
| Line 1: | Line 1: | ||
{{Seed}} | {{Seed}} | ||
| - | [[Image:3lu9. | + | [[Image:3lu9.png|left|200px]] |
<!-- | <!-- | ||
| Line 12: | Line 12: | ||
===Crystal structure of human thrombin mutant S195A in complex with the extracellular fragment of human PAR1=== | ===Crystal structure of human thrombin mutant S195A in complex with the extracellular fragment of human PAR1=== | ||
| + | |||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20236938}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20236938 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_20236938}} | ||
==Disease== | ==Disease== | ||
| Line 20: | Line 26: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:15152000</ref><references group="xtra"/> | + | <ref group="xtra">PMID:20236938</ref><ref group="xtra">PMID:15152000</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
| Line 50: | Line 56: | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:40:54 2010'' |
Revision as of 04:36, 26 May 2010
Contents |
Crystal structure of human thrombin mutant S195A in complex with the extracellular fragment of human PAR1
Template:ABSTRACT PUBMED 20236938
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
3LU9 is a 6 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gandhi PS, Chen Z, Di Cera E. Crystal structure of thrombin bound to the uncleaved extracellular fragment of PAR1. J Biol Chem. 2010 May 14;285(20):15393-8. Epub 2010 Mar 17. PMID:20236938 doi:10.1074/jbc.M110.115337
- Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:http://dx.doi.org/10.1074/jbc.M401756200
Page seeded by OCA on Wed May 26 08:40:54 2010
Categories: Homo sapiens | Thrombin | Cera, E Di. | Chen, Z. | Gandhi, P S. | Acute phase | Blood coagulation | Calcium | Cell membrane | Cleavage on pair of basic residue | Disease mutation | Disulfide bond | G-protein coupled receptor | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Kringle | Membrane | Pharmaceutical | Phosphoprotein | Polymorphism | Protease | Receptor | Secreted | Serine protease | Transducer | Transmembrane | Zymogen
