Proteopedia:Table of Contents
From Proteopedia
(Difference between revisions)
Line 175: | Line 175: | ||
*** [[Acetylcholine]] | *** [[Acetylcholine]] | ||
*** [[Flexibility of aromatic residues in acetylcholinesterase]] | *** [[Flexibility of aromatic residues in acetylcholinesterase]] | ||
- | *** [[AChE inhibitors and substrates]] | + | |
+ | |||
+ | *** [[AChE - Different Languages - inhibitors and substrates]] | ||
**** [[1eve]] AChE-Aricept complex; [[1eve (Arabic)]]; [[1eve (Chinese)]]; [[1eve (Italian)]]; [[1eve (Russian)]]; [[1eve (Spanish)]]; [[1eve (Turkish)]] | **** [[1eve]] AChE-Aricept complex; [[1eve (Arabic)]]; [[1eve (Chinese)]]; [[1eve (Italian)]]; [[1eve (Russian)]]; [[1eve (Spanish)]]; [[1eve (Turkish)]] | ||
+ | |||
+ | *** Acetylcholinesterase - AChE native | ||
+ | **** [[3lii]] – hAChE - recombinant human | ||
+ | **** [[1ea5]], [[2ace]] – ''Tc''AChE – trigonal – ''Torpedo californica'' | ||
+ | **** [[2j3d]] – ''Tc''AChE – monoclinic | ||
+ | **** [[1w75]] – ''Tc''AChE – orthorhombic | ||
+ | **** [[1eea]] – ''Tc''AChE – cubic | ||
+ | **** [[2vt6]], [[2vt7]] – ''Tc''AChE – different dosage | ||
+ | **** [[1qid]] to [[1qim]] - ''Tc''AChE synchrotron radiation damage | ||
+ | **** [[1j06]], [[1maa]] – mAChE - mouse | ||
+ | **** [[1qo9]] – ''Dm''AChE - ''Drosophila'' | ||
+ | **** [[1c2o]], [[1c2b]] – electrophorus AChE – Electric eel | ||
+ | |||
+ | *** AChE active site inhibitors conjugating at the bottom of the active site gorge | ||
+ | **** [[2w9i]] – ''Tc''AChE + methylene blue | ||
+ | **** [[2wls]] – MosAChE + AMTS13 | ||
+ | **** [[2vq6]] – ''Tc''AChE + 2-PAM | ||
+ | **** [[2j3q]] – ''Tc''AChE + Thioflavin T | ||
+ | **** [[2ha0]] – mAChE + ketoamyltrimethylammonium | ||
+ | **** [[2h9y]] – mAChE + TMTFA | ||
+ | **** [[1gpk]], [[1gpn]], [[1vot]] – ''Tc''AChE + huperzine | ||
+ | **** [[1gqr]] – ''Tc''AChE + rivastigmine | ||
+ | **** [[1gqs]] – ''Tc''AChE + NAP | ||
+ | **** [[1e66]] – ''Tc''AChE + huprine | ||
+ | **** [[1dx4]], [[1qon]] – ''Dm''AChE + tacrine derivative | ||
+ | **** [[1oce]] – ''Tc''AChE + MF268 | ||
+ | **** [[1ax9]], [[1ack]] – ''Tc''AChE + edrophonium | ||
+ | **** [[1amn]] – ''Tc''AChE + TMTFA | ||
+ | **** [[1acj]] – ''Tc''AChE + tacrine | ||
+ | |||
+ | *** AChE peripheral site inhibitors conjugating at the surface of the protein | ||
+ | **** [[1ku6]] - mAChE + fasciculin 2 | ||
+ | **** [[1ku6]], [[1mah]] - mAChE + fasciculin 2 | ||
+ | **** [[1j07]] - mAChE + decidium | ||
+ | **** [[1n5m]] - mAChE + gallamine | ||
+ | **** [[1n5r]] - mAChE + propidium | ||
+ | **** [[1b41]], [[1f8u]] - hAChE + fasciculin 2 | ||
+ | **** [[1fss]] - TcAChE + fasciculin 2 | ||
+ | |||
+ | *** AChE bis inhibitors spanning the active site gorge | ||
**** [[AChE bivalent inhibitors]] | **** [[AChE bivalent inhibitors]] | ||
+ | **** [[3i6m]] – ''Tc''AChE + N-piperidinopropyl galanthamine | ||
+ | **** [[3i6z]] - ''Tc''AChE + saccharinohexyl galanthamine | ||
+ | **** [[1zgb]], [[1zgc]] – ''Tc''AChE + tacrine (10) hupyridone | ||
+ | **** [[2w6c]] – ''Tc''AChE + bis-(-)-nor-meptazinol | ||
+ | **** [[2ckm]], [[2cmf]] – ''Tc''AChE + bis-tacrine | ||
+ | **** [[2cek]] – ''Tc''AChE + N-[8-(1,2,3,4-tetrahydroacridin-9-ylthio)octyl]-1,2,3,4-tetrahydroacridin-9-amine | ||
+ | **** [[1ut6]] - ''Tc''AChE + N-9-(1,2,3,4-tetrahydroacridinyl)-1,8-diaminooctane | ||
+ | **** [[1odc]] - ''Tc''AChE + N-4-quinolyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,8-diaminooctane | ||
+ | **** [[1w4l]], [[1w6r]], [[1w76]], [[1dx6]], [[1qti]] - TcAChE + galanthamine and derivative | ||
+ | **** [[1q83]], [[1q84]] - mAChE + TZ2PA6 | ||
+ | **** [[1h22]], [[1h23]] – ''Tc''AChE + bis-hupyridone | ||
+ | **** [[1hbj]] – ''Tc''AChE + quinoline derivativev | ||
+ | **** [[1e3q]] – ''Tc''AChE + bw284c51 | ||
+ | **** [[1eve]] – ''Tc''AChE + e2020 | ||
+ | **** [[1acl]] – ''Tc''AChE + decamethonium | ||
+ | |||
+ | |||
+ | *** AChE organophosphate inhibitors causing irreversible inhibition | ||
+ | **** [[2wu3]] – mAChE + fenamiphos and HI-6 | ||
+ | **** [[2wu4]] – mAChE + fenamiphos and ortho-7 | ||
+ | **** [[2jgf]] - mAChE + fenamiphos | ||
+ | **** [[2wfz]], [[2wg0]], [[1som]] - ''Tc''AChE + soman | ||
+ | **** [[2wg1]] - ''Tc''AChE + soman + 2-PAM | ||
+ | **** [[2whp]], [[2whq]], [[2whr]] – mAChE + sarin and HI-6 | ||
+ | **** [[2jgg]] - mAChE + sarin | ||
+ | **** [[2jgl]] - mAChE + VX and sarin | ||
+ | **** [[1cfj]] - ''Tc''AChE + sarin, GB | ||
+ | **** [[3dl4]], [[3dl7]] – mAChE + tabun | ||
+ | **** [[2jey]] – mAChE + HLO-7 | ||
+ | **** [[2c0p]], [[2c0q]] - mAChE + tabun | ||
+ | **** [[2jez]] - mAChE + tabun + HLO-7 | ||
+ | **** [[2jf0]] - mAChE + tabun + Ortho-7 | ||
+ | **** [[2jgh]] - mAChE + VX | ||
+ | **** [[1vxo]], [[1vxr]] - ''Tc''AChE + VX | ||
+ | **** [[2jgi]], [[2jgm]] - mAChE + DFP | ||
+ | **** [[1dfp]] - ''Tc''AChE + DFP | ||
+ | **** [[2jgj]], [[2jgk]], [[2jge]] - mAChE + methamidophos | ||
+ | **** [[2gyu]] - mAChE + HI-6 | ||
+ | **** [[2gyv]] - mAChE + Ortho-7 | ||
+ | **** [[2gyw]] - mAChE + obidoxime | ||
+ | |||
+ | *** AChE substrate analogues mimicking the binding of the substrate acetylcholine | ||
+ | **** [[2ha4]] – mAChE (mutant) + acetylcholine | ||
+ | **** [[2vja]], [[2vjb]], [[2vjc]], [[2vjd]], [[2cf5]] – ''Tc''AChE + 4-oxo-N,N,N-trimethylpentanaminium | ||
+ | **** [[2v96]], [[2v97]], [[2v98]], [[2v99]] – ''Tc''AChE + 1-(2-nitrophenyl)-2,2,2-trifluoroethyl-arsenocholine | ||
+ | **** [[2ha2]] – mAChE + succinylcholine | ||
+ | **** [[2ha3]] - mAChE + choline | ||
+ | **** [[2ha5]] – mAChE (mutant) + acetylthiocholine | ||
+ | **** [[2ha6]] – mAChE (mutant) + succinylthiocholine | ||
+ | **** [[2ha7]] – mAChE (mutant) + butyrylthiocholine | ||
+ | **** [[2ch4]], [[2c58]] – ''Tc''AChE + acetylthiocholine | ||
+ | **** [[2c5g]] – ''Tc''AChE + thiocholine | ||
+ | |||
+ | *** Others… | ||
+ | **** [[2j4f]] – ''Tc''AChE + Hg | ||
+ | **** [[1vzj]] – ''Tc''AChE tetramerization domain | ||
+ | **** [[1jjb]] – ''Tc''AChE + PEG | ||
+ | |||
** [[Acetylcholine binding protein]] (AChBP) | ** [[Acetylcholine binding protein]] (AChBP) |
Revision as of 05:26, 28 May 2010
This guide to the contents of Proteopedia is maintained manually (not automatically generated) and so is inevitably incomplete. Please be sure to use the search slots at the left if you don't find what you are looking for below.
Proteopedia Page Contributors and Editors (what is this?)
Joel L. Sussman, Eran Hodis, Wayne Decatur, Alexander Berchansky, Judy Voet, Alejandro Porto, Helen Ginn, David Canner, Israel Hanukoglu, Karen L. Lee, Arthur Cox, Yuan-Ping Pang, Tilman Schirmer, Eric Martz, Tomas Klumpler, Karl Oberholser, Angel Herraez, Jaime Prilusky