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3mss

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===Abl kinase in complex with imatinib and fragment (FRAG2) in the myristate site===
===Abl kinase in complex with imatinib and fragment (FRAG2) in the myristate site===
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{{ABSTRACT_PUBMED_20450175}}
==About this Structure==
==About this Structure==
3MSS is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MSS OCA].
3MSS is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MSS OCA].
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==Reference==
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<ref group="xtra">PMID:20450175</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Transferase-transferase inhibiator complex]]
[[Category: Transferase-transferase inhibiator complex]]
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Revision as of 04:21, 2 June 2010

Template:STRUCTURE 3mss

Abl kinase in complex with imatinib and fragment (FRAG2) in the myristate site

Template:ABSTRACT PUBMED 20450175

About this Structure

3MSS is a 4 chains structure with sequences from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Jahnke W, Grotzfeld RM, Pelle X, Strauss A, Fendrich G, Cowan-Jacob SW, Cotesta S, Fabbro D, Furet P, Mestan J, Marzinzik AL. Binding or bending: distinction of allosteric Abl kinase agonists from antagonists by an NMR-based conformational assay. J Am Chem Soc. 2010 May 26;132(20):7043-8. PMID:20450175 doi:10.1021/ja101837n

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