3mop
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3mop is ON HOLD Authors: Lin, S.-C., Lo, Y.-C., Wu, H. Description: The ternary Death Domain complex of MyD88, IRAK4, and IRAK2 ''Page seeded by [...) |
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| + | {{STRUCTURE_3mop| PDB=3mop | SCENE= }} | ||
| - | + | ===The ternary Death Domain complex of MyD88, IRAK4, and IRAK2=== | |
| - | Description: The ternary Death Domain complex of MyD88, IRAK4, and IRAK2 | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20485341}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20485341 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20485341}} | ||
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| + | ==Disease== | ||
| + | Known disease associated with this structure: Pyogenic bacterial infections, recurrent, due to MYD88 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602170 602170]], IRAK4 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606883 606883]], Invasive pneumococcal disease, recurrent isolated, 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606883 606883]] | ||
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| + | ==About this Structure== | ||
| + | 3MOP is a 14 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MOP OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20485341</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Lin, S C.]] | ||
| + | [[Category: Lo, Y C.]] | ||
| + | [[Category: Wu, H.]] | ||
| + | [[Category: Death domain complex]] | ||
| + | [[Category: Helical symmetry]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: Left-handed helical assembly]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Single-stranded helical assembly]] | ||
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| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:34:14 2010'' | ||
Revision as of 04:29, 2 June 2010
Contents |
The ternary Death Domain complex of MyD88, IRAK4, and IRAK2
Template:ABSTRACT PUBMED 20485341
Disease
Known disease associated with this structure: Pyogenic bacterial infections, recurrent, due to MYD88 deficiency OMIM:[602170], IRAK4 deficiency OMIM:[606883], Invasive pneumococcal disease, recurrent isolated, 1 OMIM:[606883]
About this Structure
3MOP is a 14 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lin SC, Lo YC, Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature. 2010 Jun 17;465(7300):885-90. Epub 2010 May 19. PMID:20485341 doi:10.1038/nature09121
Page seeded by OCA on Wed Jun 2 08:34:14 2010
