3lxn
From Proteopedia
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| + | {{STRUCTURE_3lxn| PDB=3lxn | SCENE= }} | ||
| - | + | ===Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6=== | |
| - | Description: Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6 | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
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| + | {{ABSTRACT_PUBMED_20478313}} | ||
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| + | ==Disease== | ||
| + | Known disease associated with this structure: Protein-tyrosine kinase 2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176941 176941]] | ||
| + | |||
| + | ==About this Structure== | ||
| + | 3LXN is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LXN OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20478313</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific protein-tyrosine kinase]] | ||
| + | [[Category: Benson, T E.]] | ||
| + | [[Category: Chrencik, J E.]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Cancer]] | ||
| + | [[Category: Inflammation]] | ||
| + | [[Category: Jak3]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Pan inhibitor]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Sh2 domain]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Tyk2]] | ||
| + | [[Category: Tyrosine-protein kinase]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:34:34 2010'' | ||
Revision as of 04:30, 2 June 2010
Contents |
Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6
Template:ABSTRACT PUBMED 20478313
Disease
Known disease associated with this structure: Protein-tyrosine kinase 2 deficiency OMIM:[176941]
About this Structure
3LXN is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Chrencik JE, Patny A, Leung IK, Korniski B, Emmons TL, Hall T, Weinberg RA, Gormley JA, Williams JM, Day JE, Hirsch JL, Kiefer JR, Leone JW, Fischer HD, Sommers CD, Huang HC, Jacobsen EJ, Tenbrink RE, Tomasselli AG, Benson TE. Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. J Mol Biol. 2010 Jul 16;400(3):413-33. Epub 2010 May 15. PMID:20478313 doi:10.1016/j.jmb.2010.05.020
Page seeded by OCA on Wed Jun 2 08:34:34 2010
