3l8w

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3l8w.jpg|left|200px]]
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The entry 3l8w is ON HOLD until Paper Publication
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{{STRUCTURE_3l8w| PDB=3l8w | SCENE= }}
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Authors: Prange, T., Gabison, L., Colloc'H, N., Chiadmi, M.
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===Urate oxidase from aspergillus flavus complexed with xanthin===
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Description: Urate oxidase from aspergillus flavus complexed with xanthin
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 16:57:37 2010''
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==About this Structure==
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3L8W is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_flavus Aspergillus flavus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L8W OCA].
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==Reference==
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<ref group="xtra">PMID:9360612</ref><ref group="xtra">PMID:16545381</ref><ref group="xtra">PMID:18638417</ref><ref group="xtra">PMID:18375516</ref><references group="xtra"/>
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[[Category: Aspergillus flavus]]
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[[Category: Urate oxidase]]
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[[Category: Chiadmi, M.]]
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[[Category: Gabison, L.]]
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[[Category: H, N Colloc.]]
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[[Category: Prange, T.]]
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[[Category: Acetylation]]
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[[Category: Inhibition aspergillus flavus]]
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[[Category: Oxidoreductase]]
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[[Category: Peroxisome]]
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[[Category: Purine metabolism]]
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[[Category: Uric acid degradation]]
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[[Category: Xanthine]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:38:47 2010''

Revision as of 04:34, 2 June 2010

Image:3l8w.jpg

Template:STRUCTURE 3l8w

Urate oxidase from aspergillus flavus complexed with xanthin

About this Structure

3L8W is a 1 chain structure with sequence from Aspergillus flavus. Full crystallographic information is available from OCA.

Reference

  • Colloc'h N, el Hajji M, Bachet B, L'Hermite G, Schiltz M, Prange T, Castro B, Mornon JP. Crystal structure of the protein drug urate oxidase-inhibitor complex at 2.05 A resolution. Nat Struct Biol. 1997 Nov;4(11):947-52. PMID:9360612
  • Gabison L, Chiadmi M, Colloc'h N, Castro B, El Hajji M, Prange T. Recapture of [S]-allantoin, the product of the two-step degradation of uric acid, by urate oxidase. FEBS Lett. 2006 Apr 3;580(8):2087-91. Epub 2006 Mar 10. PMID:16545381 doi:10.1016/j.febslet.2006.03.007
  • Gabison L, Prange T, Colloc'h N, El Hajji M, Castro B, Chiadmi M. Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: mechanistic implications. BMC Struct Biol. 2008 Jul 20;8:32. PMID:18638417 doi:10.1186/1472-6807-8-32
  • Colloc'h N, Gabison L, Monard G, Altarsha M, Chiadmi M, Marassio G, Sopkova-de Oliveira Santos J, El Hajji M, Castro B, Abraini JH, Prange T. Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism. Biophys J. 2008 Sep;95(5):2415-22. Epub 2008 Mar 28. PMID:18375516 doi:10.1529/biophysj.107.122184

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