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3mop

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{{ABSTRACT_PUBMED_20485341}}
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==Disease==
 
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Known disease associated with this structure: Pyogenic bacterial infections, recurrent, due to MYD88 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602170 602170]], IRAK4 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606883 606883]], Invasive pneumococcal disease, recurrent isolated, 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606883 606883]]
 
==About this Structure==
==About this Structure==
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[[Category: Single-stranded helical assembly]]
[[Category: Single-stranded helical assembly]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:34:14 2010''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:35:21 2010''

Revision as of 04:30, 23 June 2010

Image:3mop.png

Template:STRUCTURE 3mop

The ternary Death Domain complex of MyD88, IRAK4, and IRAK2

Template:ABSTRACT PUBMED 20485341

About this Structure

3MOP is a 14 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lin SC, Lo YC, Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature. 2010 Jun 17;465(7300):885-90. Epub 2010 May 19. PMID:20485341 doi:10.1038/nature09121

Page seeded by OCA on Wed Jun 23 08:35:21 2010

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