3mop
From Proteopedia
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Pyogenic bacterial infections, recurrent, due to MYD88 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602170 602170]], IRAK4 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606883 606883]], Invasive pneumococcal disease, recurrent isolated, 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606883 606883]] | ||
==About this Structure== | ==About this Structure== | ||
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Revision as of 04:30, 23 June 2010
The ternary Death Domain complex of MyD88, IRAK4, and IRAK2
Template:ABSTRACT PUBMED 20485341
About this Structure
3MOP is a 14 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lin SC, Lo YC, Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature. 2010 Jun 17;465(7300):885-90. Epub 2010 May 19. PMID:20485341 doi:10.1038/nature09121
Page seeded by OCA on Wed Jun 23 08:35:21 2010
