3krr

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3krr.jpg|left|200px]]
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The entry 3krr is ON HOLD until Paper Publication
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{{STRUCTURE_3krr| PDB=3krr | SCENE= }}
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Authors: Tavares, G.A., Gerspacher, M., Kroemer, M., Scheufler, C.
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===Crystal Structure of JAK2 complexed with a potent quinoxaline ATP site inhibitor===
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Description: Crystal Structure of JAK2 complexed with a potent quinoxaline ATP site inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 16 12:36:15 2009''
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{{ABSTRACT_PUBMED_20587663}}
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==About this Structure==
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3KRR is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KRR OCA].
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==Reference==
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<ref group="xtra">PMID:20587663</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Gerspacher, M.]]
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[[Category: Kroemer, M.]]
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[[Category: Scheufler, C.]]
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[[Category: Tavares, G A.]]
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[[Category: Atp site kinase inhibitor]]
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[[Category: Atp-binding]]
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[[Category: Disease mutation]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Proto-oncogene]]
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[[Category: Sh2 domain]]
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[[Category: Small molecule inhibitor]]
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[[Category: Transferase]]
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[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 10:17:16 2010''

Revision as of 06:10, 21 July 2010

Image:3krr.jpg

Template:STRUCTURE 3krr

Crystal Structure of JAK2 complexed with a potent quinoxaline ATP site inhibitor

Template:ABSTRACT PUBMED 20587663

About this Structure

3KRR is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Baffert F, Regnier CH, De Pover A, Pissot-Soldermann C, Tavares GA, Blasco F, Brueggen J, Chene P, Drueckes P, Erdmann D, Furet P, Gerspacher M, Lang M, Ledieu D, Nolan L, Ruetz S, Trappe J, Vangrevelinghe E, Wartmann M, Wyder L, Hofmann F, Radimerski T. Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805. Mol Cancer Ther. 2010 Jul;9(7):1945-55. Epub 2010 Jun 29. PMID:20587663 doi:10.1158/1535-7163.MCT-10-0053

Page seeded by OCA on Wed Jul 21 10:17:16 2010

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