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3mhc

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(New page: '''Unreleased structure''' The entry 3mhc is ON HOLD Authors: Avvaru, B.S. Description: Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of acetazol...)
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[[Image:3mhc.jpg|left|200px]]
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The entry 3mhc is ON HOLD
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{{STRUCTURE_3mhc| PDB=3mhc | SCENE= }}
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Authors: Avvaru, B.S.
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===Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of acetazolamide in a novel hydrophobic binding pocket===
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Description: Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of acetazolamide in a novel hydrophobic binding pocket
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 09:23:39 2010''
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{{ABSTRACT_PUBMED_20605094}}
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==About this Structure==
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3MHC is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MHC OCA].
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==Reference==
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<ref group="xtra">PMID:20605094</ref><references group="xtra"/>
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[[Category: Carbonate dehydratase]]
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[[Category: Homo sapiens]]
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[[Category: Avvaru, B S.]]
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[[Category: Acetazolamide]]
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[[Category: Adamantyl]]
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[[Category: Carbonic anhydrase inhibitor]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 10:19:14 2010''

Revision as of 06:12, 21 July 2010

Template:STRUCTURE 3mhc

Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of acetazolamide in a novel hydrophobic binding pocket

Template:ABSTRACT PUBMED 20605094

About this Structure

3MHC is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Avvaru BS, Wagner JM, Maresca A, Scozzafava A, Robbins AH, Supuran CT, McKenna R. Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4376-81. Epub 2010 Jun 17. PMID:20605094 doi:10.1016/j.bmcl.2010.06.082

Page seeded by OCA on Wed Jul 21 10:19:14 2010

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