1a65
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 1A65 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ | + | 1A65 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Coprinopsis_cinerea Coprinopsis cinerea]] with NAG, GLC, CU and O as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Laccase Laccase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2]]. Structure known Active Sites: T1 and T3. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1A65 OCA]]. |
==Reference== | ==Reference== | ||
Crystal structure of the type-2 Cu depleted laccase from Coprinus cinereus at 2.2 A resolution., Ducros V, Brzozowski AM, Wilson KS, Brown SH, Ostergaard P, Schneider P, Yaver DS, Pedersen AH, Davies GJ, Nat Struct Biol. 1998 Apr;5(4):310-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9546223 9546223] | Crystal structure of the type-2 Cu depleted laccase from Coprinus cinereus at 2.2 A resolution., Ducros V, Brzozowski AM, Wilson KS, Brown SH, Ostergaard P, Schneider P, Yaver DS, Pedersen AH, Davies GJ, Nat Struct Biol. 1998 Apr;5(4):310-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9546223 9546223] | ||
| - | [[Category: | + | [[Category: Coprinopsis cinerea]] |
| + | [[Category: Laccase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Brzozowski, W.]] | [[Category: Brzozowski, W.]] | ||
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[[Category: type-2 copper depleted]] | [[Category: type-2 copper depleted]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 10:49:23 2007'' |
Revision as of 08:44, 30 October 2007
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TYPE-2 CU-DEPLETED LACCASE FROM COPRINUS CINEREUS
Overview
Laccase catalyses the oxidation of a variety of organic substrates coupled, to the reduction of oxygen to water. It is widely believed to be the, simplest representative of the ubiquitous blue multi-copper oxidase, family. Laccase is implicated in a wide spectrum of biological activities, and, in particular, plays a key role in morphogenesis, development and, lignin metabolism in fungi and plants. The structure of laccase from the, fungus Coprinus cinereus has been determined by X-ray crystallography at a, resolution of 2.2 A. Laccase is a monomer composed of three, cupredoxin-like beta-sandwich domains, similar to that found in ascorbate, oxidase. In contrast to ascorbate oxidase, however, the mononuclear type-1, Cu site lacks the axial methionine ligand and so exhibits trigonal planar, ... [(full description)]
About this Structure
1A65 is a [Single protein] structure of sequence from [Coprinopsis cinerea] with NAG, GLC, CU and O as [ligands]. Active as [Laccase], with EC number [1.10.3.2]. Structure known Active Sites: T1 and T3. Full crystallographic information is available from [OCA].
Reference
Crystal structure of the type-2 Cu depleted laccase from Coprinus cinereus at 2.2 A resolution., Ducros V, Brzozowski AM, Wilson KS, Brown SH, Ostergaard P, Schneider P, Yaver DS, Pedersen AH, Davies GJ, Nat Struct Biol. 1998 Apr;5(4):310-6. PMID:9546223
Page seeded by OCA on Tue Oct 30 10:49:23 2007
Categories: Coprinopsis cinerea | Laccase | Single protein | Brzozowski, W. | Ducros, V. | CU | GLC | NAG | O | Blue multi-copper oxidase | Glycoprotein | Oxidoreductase | Signal | Type-2 copper depleted
