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Villin

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(New page: 300px {{STRUCTURE_2k6n| PDB=2k6n | SCENE= |CAPTION=Human Supervillin Headpiece, 2k6n }} '''3D Structure of Villin''' <br /> The image at the top is a human...)
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'''3D Structure of Villin''' <br />
'''3D Structure of Villin''' <br />
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The image at the top is a human Human Supervillin Headpiece (3ffn)
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The image at the top is a human Human Supervillin Headpiece ([[3ffn]])
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== Villin ==
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Villin (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin. Supervillin (SVIL) contains gelsolin-like domains in its C-terminal and interacts with actin. Advillin (AVIL) is another actin-binding protein in the gelsolin family which is expressed in the peripheral sensory neurons.
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== 3D Structures of Villin ==
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=== Supervillin ===
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[[2k6m]], [[2k6n]] – hSVIL headpiece– human – NMR<br />
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=== Villin ===
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[[3fg7]] – hVIL gelsolin domains 4-6<br />
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[[1unc]] – hVIL headpiece<br />
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[[2rjw]], [[2rjx]], [[2rjv]], [[2rjy]], [[1yu7]], [[1yu8]] – cVIL headpiece (mutant) – chicken<br />
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[[1yu5]], [[1qqv]] - cVIL headpiece<br />
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[[1vii]], [[2vik]], [[2vil]] - cVIL headpiece - NMR<br />
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[[2ppz]], [[2jm0]] - VIL headpiece (mutant) – synthetic – NMR<br />
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[[2f4k]], [[1wy3]], [[1wy4]], [[1yrf]], [[1yri]] - VIL fragment (mutant) – synthetic<br />
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== Advillin ==
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[[1und]] – hAVIL headpiece<br />

Revision as of 12:01, 22 July 2010

Template:STRUCTURE 2k6n

3D Structure of Villin
The image at the top is a human Human Supervillin Headpiece (3ffn)


Contents

Villin

Villin (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin. Supervillin (SVIL) contains gelsolin-like domains in its C-terminal and interacts with actin. Advillin (AVIL) is another actin-binding protein in the gelsolin family which is expressed in the peripheral sensory neurons.


3D Structures of Villin

Supervillin

2k6m, 2k6n – hSVIL headpiece– human – NMR


Villin

3fg7 – hVIL gelsolin domains 4-6
1unc – hVIL headpiece
2rjw, 2rjx, 2rjv, 2rjy, 1yu7, 1yu8 – cVIL headpiece (mutant) – chicken
1yu5, 1qqv - cVIL headpiece
1vii, 2vik, 2vil - cVIL headpiece - NMR
2ppz, 2jm0 - VIL headpiece (mutant) – synthetic – NMR
2f4k, 1wy3, 1wy4, 1yrf, 1yri - VIL fragment (mutant) – synthetic


Advillin

1und – hAVIL headpiece

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