2itp
From Proteopedia
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| - | [[Image:2itp. | + | [[Image:2itp.jpg|left|200px]]<br /><applet load="2itp" size="450" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2itp" size="450" color="white" frame="true" align="right" spinBox="true" | + | |
caption="2itp, resolution 2.74Å" /> | caption="2itp, resolution 2.74Å" /> | ||
'''CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AEE788'''<br /> | '''CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AEE788'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2ITP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with AEE as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] | + | 2ITP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with AEE as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] Known structural/functional Site: <scene name='pdbsite=AC1:Aee Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2ITP OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: tyrosine-protein kinase]] | [[Category: tyrosine-protein kinase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 19:33:45 2007'' |
Revision as of 17:23, 18 December 2007
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AEE788
Disease
Known diseases associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]
About this Structure
2ITP is a Single protein structure of sequence from Homo sapiens with AEE as ligand. Active as Receptor protein-tyrosine kinase, with EC number 2.7.10.1 Known structural/functional Site: . Full crystallographic information is available from OCA.
Page seeded by OCA on Tue Dec 18 19:33:45 2007
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Single protein | Boggon, T.J. | Eck, M.J. | Greulich, H. | Li, Y. | Meyerson, M. | Woo, S. | Yun, C.H. | AEE | Aee788 | Alternative splicing | Anti-oncogene | Atp-binding | Cell cycle | Disease mutation | Egfr | Epidermal growth factor | G719s | Glycoprotein | Kinase | Membrane | Nucleotide-binding | Phosphorylation | Polymorphism | Receptor | Transferase | Transmembrane | Tyrosine-protein kinase
