3jsu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{Seed}}
 +
[[Image:3jsu.jpg|left|200px]]
-
The entry 3jsu is ON HOLD until Paper Publication
+
<!--
 +
The line below this paragraph, containing "STRUCTURE_3jsu", creates the "Structure Box" on the page.
 +
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 +
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 +
or leave the SCENE parameter empty for the default display.
 +
-->
 +
{{STRUCTURE_3jsu| PDB=3jsu | SCENE= }}
-
Authors: Chitnumsub, P., Maneeruttanarungroj, C., Kamchonwongpaisan, S., Yuthavong, Y., Diagana, T.T.
+
===Quadruple mutant(N51I+C59R+S108N+I164L) plasmodium falciparum dihydrofolate reductase-thymidylate synthase(PFDHFR-TS) complexed with QN254, NADPH, and dUMP===
-
Description: Quadruple mutant(N51I+C59R+S108N+I164L) plasmodium falciparum dihydrofolate reductase-thymidylate synthase(PFDHFR-TS) complexed with QN254, NADPH, and dUMP
 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 28 12:55:32 2009''
+
<!--
 +
The line below this paragraph, {{ABSTRACT_PUBMED_20350951}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 20350951 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_20350951}}
 +
 
 +
==About this Structure==
 +
3JSU is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSU OCA].
 +
 
 +
==Reference==
 +
<ref group="xtra">PMID:20350951</ref><references group="xtra"/>
 +
[[Category: Plasmodium falciparum]]
 +
[[Category: Chitnumsub, P.]]
 +
[[Category: Diagana, T T.]]
 +
[[Category: Kamchonwongpaisan, S.]]
 +
[[Category: Maneeruttanarungroj, C.]]
 +
[[Category: Yuthavong, Y.]]
 +
[[Category: Oxidoreductase]]
 +
[[Category: Rossmann fold]]
 +
[[Category: Transferase]]
 +
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:36:36 2010''

Revision as of 08:29, 28 July 2010

Image:3jsu.jpg

Template:STRUCTURE 3jsu

Quadruple mutant(N51I+C59R+S108N+I164L) plasmodium falciparum dihydrofolate reductase-thymidylate synthase(PFDHFR-TS) complexed with QN254, NADPH, and dUMP

Template:ABSTRACT PUBMED 20350951

About this Structure

3JSU is a 2 chains structure with sequences from Plasmodium falciparum. Full crystallographic information is available from OCA.

Reference

  • Nzila A, Rottmann M, Chitnumsub P, Kiara SM, Kamchonwongpaisan S, Maneeruttanarungroj C, Taweechai S, Yeung BK, Goh A, Lakshminarayana SB, Zou B, Wong J, Ma NL, Weaver M, Keller TH, Dartois V, Wittlin S, Brun R, Yuthavong Y, Diagana TT. Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate. Antimicrob Agents Chemother. 2010 Jun;54(6):2603-10. Epub 2010 Mar 29. PMID:20350951 doi:10.1128/AAC.01526-09

Page seeded by OCA on Wed Jul 28 12:36:36 2010

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3jsu"
Personal tools