3lg4

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(New page: '''Unreleased structure''' The entry 3lg4 is ON HOLD Authors: Frey, K.M., Anderson, A.C. Description: Staphylococcus aureus V31Y, F92I mutant dihydrofolate reductase complexed with NAD...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3lg4.jpg|left|200px]]
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The entry 3lg4 is ON HOLD
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{{STRUCTURE_3lg4| PDB=3lg4 | SCENE= }}
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Authors: Frey, K.M., Anderson, A.C.
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===Staphylococcus aureus V31Y, F92I mutant dihydrofolate reductase complexed with NADPH and 5-[(3S)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine===
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Description: Staphylococcus aureus V31Y, F92I mutant dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(2,6-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:19:05 2010''
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{{ABSTRACT_PUBMED_20643959}}
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==About this Structure==
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3LG4 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LG4 OCA].
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==Reference==
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<ref group="xtra">PMID:20643959</ref><references group="xtra"/>
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[[Category: Dihydrofolate reductase]]
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[[Category: Staphylococcus aureus]]
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[[Category: Anderson, A C.]]
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[[Category: Frey, K M.]]
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[[Category: Nadp]]
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[[Category: One-carbon metabolism]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:37:06 2010''

Revision as of 08:30, 28 July 2010

Template:STRUCTURE 3lg4

Staphylococcus aureus V31Y, F92I mutant dihydrofolate reductase complexed with NADPH and 5-[(3S)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine

Template:ABSTRACT PUBMED 20643959

About this Structure

3LG4 is a 2 chains structure with sequences from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Frey KM, Georgiev I, Donald BR, Anderson AC. Predicting resistance mutations using protein design algorithms. Proc Natl Acad Sci U S A. 2010 Jul 19. PMID:20643959

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