3mf5

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3mf5.jpg|left|200px]]
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The entry 3mf5 is ON HOLD until Paper Publication
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{{STRUCTURE_3mf5| PDB=3mf5 | SCENE= }}
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Authors: Harris, S.F., Tavares, G., Ghate, M.
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===Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor===
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Description: Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:45:32 2010''
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{{ABSTRACT_PUBMED_20584604}}
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==About this Structure==
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3MF5 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MF5 OCA].
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==Reference==
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<ref group="xtra">PMID:20584604</ref><references group="xtra"/>
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[[Category: Hepatitis c virus]]
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Ghate, M.]]
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[[Category: Harris, S F.]]
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[[Category: Tavares, G.]]
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[[Category: Hcv]]
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[[Category: Hepatitis]]
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[[Category: Ns5b]]
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[[Category: Transferase]]
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[[Category: Transferase rna-dependent rna polymerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:39:09 2010''

Revision as of 08:32, 28 July 2010

Image:3mf5.jpg

Template:STRUCTURE 3mf5

Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor

Template:ABSTRACT PUBMED 20584604

About this Structure

3MF5 is a 2 chains structure with sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Yang H, Hendricks RT, Arora N, Nitzan D, Yee C, Lucas MC, Yang Y, Fung A, Rajyaguru S, Harris SF, Leveque VJ, Hang JQ, Pogam SL, Reuter D, Tavares GA. Cyclic amide bioisosterism: strategic application to the design and synthesis of HCV NS5B polymerase inhibitors. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4614-9. Epub 2010 Jun 8. PMID:20584604 doi:10.1016/j.bmcl.2010.06.008

Page seeded by OCA on Wed Jul 28 12:39:09 2010

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