2xc0

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'''Unreleased structure'''
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{{Seed}}
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[[Image:2xc0.jpg|left|200px]]
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The entry 2xc0 is ON HOLD until Paper Publication
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{{STRUCTURE_2xc0| PDB=2xc0 | SCENE= }}
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Authors: Banner, D.W., Benz, J., Schlatter, D., Anselm, L., Haap, W.
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===FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR===
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Description: Factor Xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 30 13:28:35 2010''
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The line below this paragraph, {{ABSTRACT_PUBMED_20650636}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 20650636 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20650636}}
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==About this Structure==
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2XC0 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XC0 OCA].
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==Reference==
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<ref group="xtra">PMID:20650636</ref><references group="xtra"/>
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[[Category: Coagulation factor Xa]]
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[[Category: Homo sapiens]]
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[[Category: Anselm, L.]]
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[[Category: Banner, D W.]]
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[[Category: Benz, J.]]
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[[Category: Haap, W.]]
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[[Category: Schlatter, D.]]
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[[Category: Blood clotting]]
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[[Category: Coagulation factor]]
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[[Category: Hydrolase]]
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[[Category: Hydroxylation]]
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[[Category: Serine protease]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 4 09:02:39 2010''

Revision as of 04:55, 4 August 2010

Image:2xc0.jpg

Template:STRUCTURE 2xc0

FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR

Template:ABSTRACT PUBMED 20650636

About this Structure

2XC0 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Anselm L, Banner DW, Benz J, Zbinden KG, Himber J, Hilpert H, Huber W, Kuhn B, Mary JL, Otteneder MB, Panday N, Ricklin F, Stahl M, Thomi S, Haap W. Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide] as a clinical candidate. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5313-9. Epub 2010 Jul 1. PMID:20650636 doi:10.1016/j.bmcl.2010.06.126

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