3iit

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3iit.jpg|left|200px]]
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The entry 3iit is ON HOLD until Aug 03 2011
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{{STRUCTURE_3iit| PDB=3iit | SCENE= }}
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Authors: Suzuki, M.
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===Factor XA in complex with a cis-1,2-diaminocyclohexane derivative===
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Description: Factor XA in complex with a cis-1,2-diaminocyclohexane derivative
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:46:11 2009''
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{{ABSTRACT_PUBMED_19900814}}
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==About this Structure==
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3IIT is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IIT OCA].
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==Reference==
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<ref group="xtra">PMID:19900814</ref><references group="xtra"/>
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[[Category: Coagulation factor Xa]]
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[[Category: Homo sapiens]]
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[[Category: Suzuki, M.]]
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[[Category: Blood coagulation]]
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[[Category: Blood coagulation factor]]
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[[Category: Calcium-binding]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Disulfide bond]]
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[[Category: Egf-like domain]]
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[[Category: Gamma-carboxyglutamic acid]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Hydroxylation]]
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[[Category: Plasma]]
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[[Category: Protease]]
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[[Category: Protein inhibitor complex]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 4 09:06:20 2010''

Revision as of 04:59, 4 August 2010

Image:3iit.jpg

Template:STRUCTURE 3iit

Factor XA in complex with a cis-1,2-diaminocyclohexane derivative

Template:ABSTRACT PUBMED 19900814

About this Structure

3IIT is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yoshikawa K, Kobayashi S, Nakamoto Y, Haginoya N, Komoriya S, Yoshino T, Nagata T, Mochizuki A, Watanabe K, Suzuki M, Kanno H, Ohta T. Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties. Bioorg Med Chem. 2009 Dec 15;17(24):8221-33. Epub 2009 Oct 17. PMID:19900814 doi:10.1016/j.bmc.2009.10.024

Page seeded by OCA on Wed Aug 4 09:06:20 2010

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