3o5x

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(New page: '''Unreleased structure''' The entry 3o5x is ON HOLD Authors: Zhang, Z-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C., Wu, L, Gunawan, A. M., Wang, L, Cha...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3o5x.jpg|left|200px]]
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The entry 3o5x is ON HOLD
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{{STRUCTURE_3o5x| PDB=3o5x | SCENE= }}
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Authors: Zhang, Z-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C., Wu, L, Gunawan, A. M., Wang, L, Chan, R. J.
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===Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor===
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Description: Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 4 08:54:26 2010''
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{{ABSTRACT_PUBMED_20170098}}
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==About this Structure==
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3O5X is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3jrl 3jrl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O5X OCA].
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==Reference==
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<ref group="xtra">PMID:20170098</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Chan, R J.]]
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[[Category: Dong, Y.]]
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[[Category: Gunawan, A M.]]
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[[Category: He, Y.]]
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[[Category: Jiang, Z.]]
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[[Category: Liu, S.]]
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[[Category: Nabinger, S C.]]
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[[Category: Wang, L.]]
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[[Category: Wu, L.]]
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[[Category: Yang, Z.]]
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[[Category: Yu, Z.]]
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[[Category: Zhang, X.]]
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[[Category: Zhang, Z Y.]]
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[[Category: Binding affinity]]
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[[Category: Binding selectivity]]
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[[Category: Dephosphorylation]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Receptor]]
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[[Category: Shp2-iib-08 complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 11 23:43:46 2010''

Revision as of 19:36, 11 August 2010

Image:3o5x.jpg

Template:STRUCTURE 3o5x

Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor

Template:ABSTRACT PUBMED 20170098

About this Structure

3O5X is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3jrl. Full crystallographic information is available from OCA.

Reference

  • Zhang X, He Y, Liu S, Yu Z, Jiang ZX, Yang Z, Dong Y, Nabinger SC, Wu L, Gunawan AM, Wang L, Chan RJ, Zhang ZY. Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2). J Med Chem. 2010 Feb 19. PMID:20170098 doi:10.1021/jm901645u

Page seeded by OCA on Wed Aug 11 23:43:46 2010

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