3inl

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===Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with agonist Alda-1===
===Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with agonist Alda-1===
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{{ABSTRACT_PUBMED_20062057}}
==About this Structure==
==About this Structure==
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3INL is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INL OCA].
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3INL is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INL OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:18787169</ref><references group="xtra"/>
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<ref group="xtra">PMID:20062057</ref><ref group="xtra">PMID:18787169</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hurley, T D.]]
[[Category: Hurley, T D.]]
[[Category: Perez-Miller, S.]]
[[Category: Perez-Miller, S.]]
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[[Category: Acetylation]]
 
[[Category: Activator]]
[[Category: Activator]]
[[Category: Alda-1]]
[[Category: Alda-1]]
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[[Category: Nad]]
[[Category: Nad]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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[[Category: Polymorphism]]
 
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
[[Category: Transit peptide]]
[[Category: Transit peptide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 14:27:55 2010''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Aug 12 00:06:38 2010''

Revision as of 19:59, 11 August 2010

Image:3inl.png

Template:STRUCTURE 3inl

Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with agonist Alda-1

Template:ABSTRACT PUBMED 20062057

About this Structure

3INL is a 8 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Perez-Miller S, Younus H, Vanam R, Chen CH, Mochly-Rosen D, Hurley TD. Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant. Nat Struct Mol Biol. 2010 Feb;17(2):159-64. Epub 2010 Jan 10. PMID:20062057 doi:10.1038/nsmb.1737
  • Chen CH, Budas GR, Churchill EN, Disatnik MH, Hurley TD, Mochly-Rosen D. Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart. Science. 2008 Sep 12;321(5895):1493-5. PMID:18787169 doi:321/5895/1493

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