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3mxw

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==Disease==
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Known disease associated with this structure: Coloboma, ocular OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600725 600725]], Holoprosencephaly-3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600725 600725]], Microphthalmia, isolated, with coloboma 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600725 600725]], Solitary median maxillary central incisor OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600725 600725]]
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The line below this paragraph, {{ABSTRACT_PUBMED_20504762}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 20504762 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20504762}}
==About this Structure==
==About this Structure==
3MXW is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXW OCA].
3MXW is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXW OCA].
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==Reference==
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<ref group="xtra">PMID:20504762</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hymowitz, S G.]]
[[Category: Hymowitz, S G.]]
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[[Category: Zinc hydrolase]]
[[Category: Zinc hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:35:47 2010''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Aug 12 00:12:57 2010''

Revision as of 20:05, 11 August 2010

Image:3mxw.png

Template:STRUCTURE 3mxw

Crystal structure Sonic hedgehog bound to the 5E1 fab fragment

Template:ABSTRACT PUBMED 20504762

About this Structure

3MXW is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Maun HR, Wen X, Lingel A, de Sauvage FJ, Lazarus RA, Scales SJ, Hymowitz SG. Hedgehog pathway antagonist 5E1 binds hedgehog at the pseudo-active site. J Biol Chem. 2010 Aug 20;285(34):26570-80. Epub 2010 May 26. PMID:20504762 doi:10.1074/jbc.M110.112284

Page seeded by OCA on Thu Aug 12 00:12:57 2010

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