3nox
From Proteopedia
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===Crystal structure of human DPP-IV in complex with Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)(morpholino)methanone=== | ===Crystal structure of human DPP-IV in complex with Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)(morpholino)methanone=== | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_20684603}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20684603 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20684603}} | ||
==About this Structure== | ==About this Structure== | ||
3NOX is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NOX OCA]. | 3NOX is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NOX OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20684603</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Klei, H E.]] | [[Category: Klei, H E.]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 11 | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:02:58 2010'' |
Revision as of 06:55, 18 August 2010
Crystal structure of human DPP-IV in complex with Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)(morpholino)methanone
Template:ABSTRACT PUBMED 20684603
About this Structure
3NOX is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Meng W, Brigance RP, Chao HJ, Fura A, Harrity T, Marcinkeviciene J, O'Connor SP, Tamura JK, Xie D, Zhang Y, Klei HE, Kish K, Weigelt CA, Turdi H, Wang A, Zahler R, Kirby MS, Hamann LG. Discovery of 6-(Aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2- carboxamides as potent, selective dipeptidyl peptidase-4 (DPP4) inhibitors. J Med Chem. 2010 Aug 12;53(15):5620-8. PMID:20684603 doi:10.1021/jm100634a
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