3mj1

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Revision as of 06:59, 18 August 2010

Template:STRUCTURE 3mj1

X-ray crystal structure of ITK complexed with inhibitor RO5191614

Template:ABSTRACT PUBMED 20545945

About this Structure

3MJ1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kutach AK, Villasenor AG, Lam D, Belunis C, Janson C, Lok S, Hong LN, Liu CM, Deval J, Novak TJ, Barnett JW, Chu W, Shaw D, Kuglstatter A. Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: insights into rational drug design and activity regulation. Chem Biol Drug Des. 2010 Aug;76(2):154-63. Epub 2010 Jun 9. PMID:20545945 doi:10.1111/j.1747-0285.2010.00993.x

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