3oc0

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(New page: '''Unreleased structure''' The entry 3oc0 is ON HOLD Authors: Hennig, M., Stihle, M., Thoma, R. Description: Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-butyl-9,10-dimethoxy-...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3oc0.jpg|left|200px]]
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The entry 3oc0 is ON HOLD
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{{STRUCTURE_3oc0| PDB=3oc0 | SCENE= }}
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Authors: Hennig, M., Stihle, M., Thoma, R.
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===Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine===
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Description: Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:26:33 2010''
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{{ABSTRACT_PUBMED_20031405}}
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==About this Structure==
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3OC0 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3kwh 3kwh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OC0 OCA].
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==Reference==
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<ref group="xtra">PMID:20031405</ref><references group="xtra"/>
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[[Category: Dipeptidyl-peptidase IV]]
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[[Category: Homo sapiens]]
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[[Category: Hennig, M.]]
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[[Category: Stihle, M.]]
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[[Category: Thoma, R.]]
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[[Category: Aminopeptidase]]
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[[Category: Cell membrane]]
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[[Category: Diabetes type ii]]
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[[Category: Disulfide bond]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Protease]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Signal-anchor]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:44:19 2010''

Revision as of 04:36, 25 August 2010

Template:STRUCTURE 3oc0

Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine

Template:ABSTRACT PUBMED 20031405

About this Structure

3OC0 is a 2 chains structure with sequences from Homo sapiens. This structure supersedes the now removed PDB entry 3kwh. Full crystallographic information is available from OCA.

Reference

  • Mattei P, Boehringer M, Di Giorgio P, Fischer H, Hennig M, Huwyler J, Kocer B, Kuhn B, Loeffler BM, Macdonald A, Narquizian R, Rauber E, Sebokova E, Sprecher U. Discovery of carmegliptin: a potent and long-acting dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1109-13. Epub 2009 Dec 6. PMID:20031405 doi:10.1016/j.bmcl.2009.12.024

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