3h9f

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===Crystal Structure of Human Dual Specificity Protein Kinase (TTK) in complex with a pyrimido-diazepin ligand===
===Crystal Structure of Human Dual Specificity Protein Kinase (TTK) in complex with a pyrimido-diazepin ligand===
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{{ABSTRACT_PUBMED_20383151}}
==About this Structure==
==About this Structure==
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3H9F is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H9F OCA].
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3H9F is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H9F OCA].
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==Reference==
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<ref group="xtra">PMID:20383151</ref><references group="xtra"/>
[[Category: Dual-specificity kinase]]
[[Category: Dual-specificity kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Fedorov, O.]]
[[Category: Fedorov, O.]]
[[Category: Filippakopoulos, P.]]
[[Category: Filippakopoulos, P.]]
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[[Category: Grey, N.]]
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[[Category: Gray, N S.]]
[[Category: Keates, T.]]
[[Category: Keates, T.]]
[[Category: King, O.]]
[[Category: King, O.]]
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[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Phosphotyrosine picked threonine kinase]]
[[Category: Phosphotyrosine picked threonine kinase]]
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[[Category: Polymorphism]]
 
[[Category: Pyt]]
[[Category: Pyt]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
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[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 19:16:52 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:26:00 2010''

Revision as of 05:17, 1 September 2010

Template:STRUCTURE 3h9f

Crystal Structure of Human Dual Specificity Protein Kinase (TTK) in complex with a pyrimido-diazepin ligand

Template:ABSTRACT PUBMED 20383151

About this Structure

3H9F is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kwiatkowski N, Jelluma N, Filippakopoulos P, Soundararajan M, Manak MS, Kwon M, Choi HG, Sim T, Deveraux QL, Rottmann S, Pellman D, Shah JV, Kops GJ, Knapp S, Gray NS. Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat Chem Biol. 2010 May;6(5):359-68. Epub 2010 Apr 11. PMID:20383151 doi:10.1038/nchembio.345

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