2xdx

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(New page: '''Unreleased structure''' The entry 2xdx is ON HOLD Authors: Murray, C.W., Carr, M.G., Callaghan, O., Chessari, G., Congreve, M., Cowan, S., Coyle, J.E., Downham, R., Figueroa, E., Fre...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:2xdx.jpg|left|200px]]
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The entry 2xdx is ON HOLD
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{{STRUCTURE_2xdx| PDB=2xdx | SCENE= }}
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Authors: Murray, C.W., Carr, M.G., Callaghan, O., Chessari, G., Congreve, M., Cowan, S., Coyle, J.E., Downham, R., Figueroa, E., Frederickson, M., Graham, B., McMenamin, R., OBrien, M.A., Patel, S., Phillips, T.R., Williams, G., Woodhead, A.J., Woolford, A.J.A.
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===STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND===
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Description: Structre of HSP90 with small molecule inhibitor bound
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 09:13:05 2010''
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(as it appears on PubMed at http://www.pubmed.gov), where 20718493 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20718493}}
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==About this Structure==
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2XDX is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XDX OCA].
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==Reference==
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<ref group="xtra">PMID:20718493</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Callaghan, O.]]
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[[Category: Carr, M G.]]
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[[Category: Chessari, G.]]
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[[Category: Congreve, M.]]
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[[Category: Cowan, S.]]
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[[Category: Coyle, J E.]]
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[[Category: Downham, R.]]
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[[Category: Figueroa, E.]]
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[[Category: Frederickson, M.]]
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[[Category: Graham, B.]]
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[[Category: Mcmenamin, R.]]
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[[Category: Murray, C W.]]
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[[Category: Obrien, M A.]]
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[[Category: Patel, S.]]
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[[Category: Phillips, T R.]]
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[[Category: Williams, G.]]
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[[Category: Woodhead, A J.]]
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[[Category: Woolford, A J.A.]]
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[[Category: Chaperone]]
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[[Category: Inhibitor]]
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[[Category: Stress response]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:45:54 2010''

Revision as of 05:37, 1 September 2010

Template:STRUCTURE 2xdx

STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND

Template:ABSTRACT PUBMED 20718493

About this Structure

2XDX is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Murray CW, Carr MG, Callaghan O, Chessari G, Congreve M, Cowan S, Coyle JE, Downham R, Figueroa E, Frederickson M, Graham B, McMenamin R, O'Brien MA, Patel S, Phillips TR, Williams G, Woodhead AJ, Woolford AJ. Fragment-based drug discovery applied to hsp90. Discovery of two lead series with high ligand efficiency. J Med Chem. 2010 Aug 26;53(16):5942-55. PMID:20718493 doi:10.1021/jm100059d

Page seeded by OCA on Wed Sep 1 09:45:54 2010

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