3lco

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3lco.jpg|left|200px]]
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The entry 3lco is ON HOLD until sometime in the future
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{{STRUCTURE_3lco| PDB=3lco | SCENE= }}
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Authors: Kamtekar, S., Day, J.E., Reitz, B.A., Mathis, K.J., Meyers, M.J.
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===Inhibitor Bound to A DFG-Out structure of the Kinase Domain of CSF-1R===
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Description: Inhibitor Bound to A DFG-Out structure of the Kinase Domain of CSF-1R
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 24 08:36:33 2010''
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{{ABSTRACT_PUBMED_20137931}}
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==About this Structure==
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3LCO is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCO OCA].
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==Reference==
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<ref group="xtra">PMID:20137931</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Day, J E.]]
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[[Category: Kamtekar, S.]]
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[[Category: Mathis, K J.]]
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[[Category: Meyers, M J.]]
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[[Category: Reitz, B A.]]
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[[Category: Atp-binding]]
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[[Category: Disulfide bond]]
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[[Category: Glycoprotein]]
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[[Category: Immunoglobulin domain]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Proto-oncogene]]
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[[Category: Receptor]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:48:48 2010''

Revision as of 07:40, 15 September 2010

Image:3lco.jpg

Template:STRUCTURE 3lco

Inhibitor Bound to A DFG-Out structure of the Kinase Domain of CSF-1R

Template:ABSTRACT PUBMED 20137931

About this Structure

3LCO is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Meyers MJ, Pelc M, Kamtekar S, Day J, Poda GI, Hall MK, Michener ML, Reitz BA, Mathis KJ, Pierce BS, Parikh MD, Mischke DA, Long SA, Parlow JJ, Anderson DR, Thorarensen A. Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1543-7. Epub 2010 Jan 21. PMID:20137931 doi:10.1016/j.bmcl.2010.01.078

Page seeded by OCA on Wed Sep 15 10:48:48 2010

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