Titin
From Proteopedia
| Line 24: | Line 24: | ||
[[2a38]] - hTTN residues 1-194<br /> | [[2a38]] - hTTN residues 1-194<br /> | ||
[[1g1c]] - hTTN residues 2027-2125<br /> | [[1g1c]] - hTTN residues 2027-2125<br /> | ||
| - | [[1h8b]] – rTTN residues 648-698+h | + | [[1h8b]] – rTTN residues 648-698+h α Actinin 2 EF hands 3&4<br /> |
[[1bpv]] – hTTN A71 – NMR<br /> | [[1bpv]] – hTTN A71 – NMR<br /> | ||
[[1tki]] – hTTN serine kinase fragment<br /> | [[1tki]] – hTTN serine kinase fragment<br /> | ||
[[1nct]], [[1ncu]] – hTTN M5 – NMR<br /> | [[1nct]], [[1ncu]] – hTTN M5 – NMR<br /> | ||
[[1tnm]], [[1tnn]] – hTTN M5<br /> | [[1tnm]], [[1tnn]] – hTTN M5<br /> | ||
Revision as of 13:30, 16 September 2010
Titin (TTN) is the largest known protein. The human TTN contains 34,350 residues. It is responsible for the passive elasticity of muscle. It has 244 domains connected by unstructured regions. The domains unfold when TTN is stretched. The images at the left and at the right correspond to one representative titin, i.e. the crystal structure of I-band fragment I67-I69 from rabbit titin (2rik).
Contents |
3D Structures of Titin
2wp3, 2wwm, 3knb – hTTN residues 34252-34350+obscuring-like protein 1 fragment – human
2wwk - hTTN residues 34252-34350+obscuring-like protein 1 fragment (mutant)
2rq8 – hTTN residues 12677-12765 (mutant) – NMR
1tit, 1tiu - hTTN I27 – NMR
2rik – rTTN I67-I69 – rabbit
2rjm - rTTN I67-I69 (mutant)
3b43 - rTTN I65-I70
2j8h, 2j8o, 2ill – hTTN residues 24430-24623
2nzi – hTTN residues 31854-32155
2bk8 – hTTN residues 25073-25166
1waa - hTTN residues 12801-12889
2f8v, 1ya5 - hTTN residues 1-196+telethonin
2a38 - hTTN residues 1-194
1g1c - hTTN residues 2027-2125
1h8b – rTTN residues 648-698+h α Actinin 2 EF hands 3&4
1bpv – hTTN A71 – NMR
1tki – hTTN serine kinase fragment
1nct, 1ncu – hTTN M5 – NMR
1tnm, 1tnn – hTTN M5
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, David Canner, Jaime Prilusky
