This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2w0x
From Proteopedia
(Difference between revisions)
| Line 12: | Line 12: | ||
===FACTOR INHIBITING HIF-1 ALPHA WITH PYRIDINE 2,4 DICARBOXYLIC ACID=== | ===FACTOR INHIBITING HIF-1 ALPHA WITH PYRIDINE 2,4 DICARBOXYLIC ACID=== | ||
| + | |||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20822901}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20822901 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_20822901}} | ||
==About this Structure== | ==About this Structure== | ||
| Line 17: | Line 23: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:12446723</ref><references group="xtra"/> | + | <ref group="xtra">PMID:20822901</ref><ref group="xtra">PMID:12446723</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Peptide-aspartate beta-dioxygenase]] | [[Category: Peptide-aspartate beta-dioxygenase]] | ||
| Line 25: | Line 31: | ||
[[Category: Mcdonough, M A.]] | [[Category: Mcdonough, M A.]] | ||
[[Category: Schofield, C J.]] | [[Category: Schofield, C J.]] | ||
| - | [[Category: 2-oxoglutarate]] | ||
| - | [[Category: Asparaginyl hydroxylase]] | ||
[[Category: Dioxygenase]] | [[Category: Dioxygenase]] | ||
| - | [[Category: Dsbh]] | ||
| - | [[Category: Fih]] | ||
| - | [[Category: Hif]] | ||
[[Category: Hydroxylase]] | [[Category: Hydroxylase]] | ||
[[Category: Hypoxia]] | [[Category: Hypoxia]] | ||
| - | [[Category: Iron]] | ||
| - | [[Category: Metal-binding]] | ||
| - | [[Category: Nucleus]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
| - | [[Category: Oxygenase]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription activator/inhibitor]] | [[Category: Transcription activator/inhibitor]] | ||
| - | [[Category: Transcription regulation]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:20:30 2010'' |
Revision as of 11:11, 22 September 2010
FACTOR INHIBITING HIF-1 ALPHA WITH PYRIDINE 2,4 DICARBOXYLIC ACID
Template:ABSTRACT PUBMED 20822901
About this Structure
2W0X is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Conejo-Garcia A, McDonough MA, Loenarz C, McNeill LA, Hewitson KS, Ge W, Lienard BM, Schofield CJ, Clifton IJ. Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6125-8. Epub 2010 Aug 10. PMID:20822901 doi:10.1016/j.bmcl.2010.08.032
- Elkins JM, Hewitson KS, McNeill LA, Seibel JF, Schlemminger I, Pugh CW, Ratcliffe PJ, Schofield CJ. Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha. J Biol Chem. 2003 Jan 17;278(3):1802-6. Epub 2002 Nov 21. PMID:12446723 doi:http://dx.doi.org/10.1074/jbc.C200644200
Page seeded by OCA on Wed Sep 22 14:20:30 2010
